At a glance
- Common name: Palmitoylethanolamide (PEA)
- Class: N-acylethanolamine (endogenous fatty-acid amide)
- Form: Powder; ask about particle-size options for your application
- Item Code: 5959
What PEASure™ Is
PEA is an endogenous lipid mediator belonging to the N-acylethanolamine (NAE) family. It is synthesized on demand within cell membranes in response to stress or injury and acts locally within tissues, including the brain. PEA is also present in trace amounts in foods such as eggs, peanuts, and soy lecithin, but at levels far below the systemic doses studied in clinical work. PEASure™ is supplied as a high-purity ingredient suited for capsule, tablet, sachet, and beverage applications.
Mechanism
PEA’s primary identified mechanism is activation of the nuclear receptor PPAR-α, which down-modulates inflammatory gene expression and contributes to neuroprotection. PEA also indirectly modulates the endocannabinoid system through engagement with CB1 and CB2 receptors and interacts with newer molecular targets including GPR55 and TRPV1. Importantly, PEA does not produce psychoactive effects and is structurally distinct from cannabinoids — it has its own well-characterized non-cannabinoid pathway.
Why Formulators Choose PEASure™
- A clearly characterized, non-psychoactive endogenous compound with growing peer-reviewed literature.
- Long-established safety profile in published research.
- Powder format compatible with capsules, tablets, stick packs, and gummies.
- Differentiation in comfort, recovery, and immune categories without controlled-substance complexity.
Where PEASure™ Fits
Dosage formats: capsules, tablets, stick packs, gummies, sublingual powders, beverages.
Industries served: dietary supplements; sports nutrition; veterinary / pet nutrition (well-established in companion-animal applications).
Technical Specifications
Request the current specification and lot-specific certificate of analysis for your selected grade.
| Detail | Information |
|---|---|
| Item Code | 5959 |
| Common Name | Palmitoylethanolamide (PEA) |
For standardization, form, appearance, particle size, loss on drying, heavy metals, microbiology, allergens, gmo status, shelf life, request the current product documentation.
Ordering Information
| Detail | Information |
|---|---|
| Standard packaging | Confirm the available pack size with your quote |
| MOQ | Quoted for the selected ingredient and order quantity |
| Lead time | Request current availability and delivery timing |
| Sample availability | Yes |
Quality, Compliance & Certifications
Request current certificates and product statements for the selected grade; certification availability is subject to verification.
- Distributed under cGMP and the GCI Sure™ program.
- Request the current specification and lot-specific certificate of analysis.
Often Formulated With
- Curcumin, boswellia, omega-3 — comfort and recovery stacks.
- CBD-adjacent and endocannabinoid-system formulations [confirm regulatory status by region].
- Magnesium, B-complex, melatonin — sleep and recovery formulations.
Resources
- PEASure™ specification — request through the technical documents form
- Current COA — request via form
- Dr. Koz’s Corner: endocannabinoid and PPAR-α topics
Bring PEASure™ Into Your Next Formulation
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent disease. PEASure™ is a trademark of GCI Nutrients, Inc.